Experimental Infection of Reindeer with Cervid Herpesvirus 2

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Cervid herpesvirus 2 causes respiratory and fetal infections in semidomesticated reindeer.

Members of the viral subfamily Alphaherpesvirinae establish latency from which they can be reactivated. Bovine herpesvirus 1 causes infectious bovine rhinotracheitis and infectious pustular vulvovaginitis in cattle, as well as abortion and weak calves. Serological evidence of alphaherpesvirus infection has been reported for wild and semidomesticated reindeer (Rangifer tarandus tarandus) in Norw...

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Cervid herpesvirus 2 and not Moraxella bovoculi caused keratoconjunctivitis in experimentally inoculated semi-domesticated Eurasian tundra reindeer

BACKGROUND Infectious keratoconjunctivitis (IKC) is a transmissible disease in semi-domesticated Eurasian reindeer (Rangifer tarandus tarandus). It is regarded as multifactorial and a single causative pathogen has not yet been identified. From clinical outbreaks we have previously identified Cervid herpesvirus 2 (CvHV2) and Moraxella bovoculi as candidates for experimental investigations. Eight...

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Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus): microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2

BACKGROUND Infectious keratoconjunctivitis (IKC) is one of the most common ocular diseases in ruminants worldwide. In addition to keratitis and conjunctivitis, animals with IKC can develop uveitis, corneal ulcer, and in severe cases, blindness. The bacteria Moraxella spp. has been described as the primary causative agent of infectious bovine keratoconjunctivitis (IBK) in cattle (Bos taurus), wh...

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Experimental infection of sheep with ovine herpesvirus 2 via aerosolization of nasal secretions.

Ovine herpesvirus 2 (OvHV-2) is the causative agent of sheep-associated malignant catarrhal fever in clinically susceptible ruminants, including cattle, bison and deer. Studies of OvHV-2 have been hampered by the lack of an in vitro propagation system. Here, the use of nasal secretions collected from OvHV-2-infected sheep experiencing intense virus shedding episodes as a source of infectious vi...

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Experimental infection of rabbits with ovine herpesvirus 2 from sheep nasal secretions.

Malignant catarrhal fever (MCF) is a generally fatal disease that primarily occurs in ruminants and is caused by a group of gammaherpesviruses. Outside of Africa MCF is mainly caused by ovine herpesvirus 2 (OvHV-2) which is carried subclinically by sheep. Cell-free virus is present in nasal secretions of shedding sheep and aerosol is the primary mode of transmission. Although OvHV-2 has never b...

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ژورنال

عنوان ژورنال: Clinical and Vaccine Immunology

سال: 2009

ISSN: 1556-6811,1556-679X

DOI: 10.1128/cvi.00218-09